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a set of pharmacologic features that make certain drugs particularly hazardous for patients over 65 years of age.

A list of such drugs was first published in 1991 and has been periodically revised by specialists in geriatrics.

Liberalizing diets helps avoid unintentional weight loss in nursing home residents, although the use of feeding tubes usually does not improve nutrition or decrease aspiration risk.

Medical assessment, treatment of comorbidities, and appropriate use of rehabilitation therapies minimize the frequency of falls.

Toileting programs may be used to treat incontinence and retention in cooperative patients.

Adverse effects and drug interactions should be considered when initiating pharmacologic treatment of overactive bladder.

“There are a lot of drug-drug interactions, but we’ve narrowed this list down to clinically meaningful and impactful information,” incoming ASCP president Nicole Brandt, Pharm D, MBA, CGP, BCPP, FASCP, told session attendees.

Prescription drug use by the elderly can often result in adverse drug events that contribute to hospitalization, increased duration of illness, nursing home placement, falls and fractures.

Our prescribing privilege is a powerful tool to help heal our patients and a toxic means to harm them if we are careless, lack knowledge of potential drug interactions, or disregard this knowledge.

More than 3200 prescription drugs, 300 dietary supplements, and 600 herbal products occupy pharmacy shelves in the United States, This creates a regrettable scenario when we write prescriptions for patients with whom we have little history, we see in our partners’ absence, or we rush to treat in a busy emergency department with the goal of easing disease while assuring safety in our treatment methods. However, for patients taking two medications, the risk of a drug interaction is 15%.

People with the greatest burden of adverse medication and polypharmacy are generally aged over 80 years, with multiple co-morbid conditions and a life expectancy of 3 years or less.

In these patients, the risk of ADRs increases in proportion to the number of simultaneous prescription drugs [ 5 ].


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